
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 643597.

ClinicalTrials.gov Identifier:
NCT02527629
News

Möglichkeiten des Aortenklappenersatzes beim jungen Erwachsenen: dezellularisierte menschliche Spenderklappen
Options for aortic valve replacement in young adults: decellularized human donor valves A new article has been published summarizing the options for young patient facing the need for aortic valve replacement. The article...

5-year results of the prospective ARISE Study will be presented at the 37th Annual Meeting of the EACTS in Vienna
The ARISE consortium partners will present results of the prospective European trial on decellularized allografts for aortic valve replacement at the upcoming EACTS meeting in Vienna, which will be held from 4-7th of October...

Update on decellularized homografts for double semilunar valve replacement
Bobylev et al published an update on the Hannover Medical School experience in simultaneous double semilunar valve replacement in congenital heart disease. Decellularized homografts were used for double valve replacement as well...
Welcome to ARISE
65,000 aortic valve replacements (AVR) are performed in Europe each year to treat acquired and congenital aortic valve diseases. Current AVR options are, however, limited for young patients - especially female patients - and those unwilling to accept life-long medical anticoagulation with its inherent risks. None of the currently available prostheses for AVR is tailored toward the individual patient or allows for individual regeneration. The ARISE project will bridge this therapeutic gap in a clinical study to determine the feasibility, safety and efficacy of regenerative heart valves for aortic valve replacement.