Press releases

16 March 2023

Update on decellularized homografts for double semilunar valve replacement

Bobylev et al published an update on the Hannover Medical School experience in simultaneous double semilunar valve replacement in congenital heart disease. Decellularized homografts were used for double valve replacement as well...

28 January 2022

Long decellularized valved aortic homografts restore normal hemodynamics

A 4D-Flow CMR study on decellularized allografts for extended aortic valve replacement was recently published within the European Journal of Cardiothoracic Surgery. Cvitkovic et al. demonstrate within this publication near...

22 February 2021

Newly developed method helps to quantify the residual immunogenic potential of decellularized human heart valves

Dot-blot techniques demonstrate highly individual immune response towards decellularized homografts - Results published Open Access in the European Journal of Cardio-Thoracic-Surgery

25 June 2020

Results of the first 106 pediatric patients published– Open Acces in the European Journal of Cardio-Thoracic Surgery

The results of the first 106 pediatric implantations of a decellularised aortic homograft have been published now and are available Open Access under this permanent link:

25 June 2020

Initial results of the ARISE trial published in the European Journal of Cardio-Thoracic Surgery – Open Acces

Initial results from the ARISE trial, a prospective, single-arm European study on decellularized allografts for aortic valve replacement now have been published and are available Open Access under this permanent link:

22 July 2019

Presentation of the early ARISE results at the 2019 Meeting of the European Association for Cardio-Thoracic-Surgery (EACTS) Saturday 5th of October in Lisbon, Portugal

Results for pediatric aortic valve replacement using cell-free homografts will be presented as well at the EACTS 2019 [more]

18 March 2019

ARISE closing meeting held on 1st of March 2019 in Hannover - Early results from the prospective European trial on cell-free allografts for aortic valve replacement

Aortic valve replacement (AVR) in children and young adult patients still constitutes a major problem as these young individuals face a difficult choice between a complex, multi-valve procedure such as the Ross-procedure and the... [more]

15 February 2019

Patient lecture and seminar on regenerative heart valves and stem cell therapy options - 30.03.2019 in the Hannover Zoo

Patientenseminar: Regenerative Therapien und Stammzelltherapie bei angeborenen Herzfehlern – geht das schon? [more]

15 October 2018

DGFG publishes film on heart valve donation

Please find the film in german language here. [more]

01 October 2018

ARISE Trial inclusion completed – calculated sample size exceeded by participating hospitals

120 implantations was the calculated sample size for the ARISE study, which is trialing a novel type of graft – cell-free aortic homografts- for the replacement of aortic valves. 8 participating hospitals managed to include 138... [more]

01 October 2018

World Heart Day Information by the European Commission – Rebuilding young lives with cell-free heart valves

The ARISE project has been chosen as a theme for the World Heart Day information campaign by the European Commission. The report can be found here. [more]

12 June 2018

Neuer Artikel in der HAZ

Hier finden Sie den Artikel Wie eine Gewebespende diesem 26-Jńhrigen das Leben rettete vom 6. Juni 2018. [more]

21 December 2017

Report on the training workshop for surgeons

Please find the Report on the training workshop for surgeons in Barcelona hier. [more]

28 November 2017

ARISE clinical study presented at the 31st Annual Meeting of the European Association For Cardio-Thoracic Surgery (EACTS) 2017 in Vienna

Brazilian group reports results of decellularised allografts used for RVOT construction during the ROSS operation Training workshop for young surgeons held in Barcelona in November 2017 Prof. Dr. Samir Sarikouch presented the... [more]

07 August 2017

ARISE Clinical Trial half-time on the road

Patient inclusion to the ARISE trial is proceeding nicely. Figure 1 is showing the numbers of patients operated within the trial already as well as the number of scheduled operations. Therefore the ARISE consortium is confident... [more]

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